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Mebendazole is an anthelmintic medication widely used to treat infections caused by intestinal parasites in humans. It is effective against a variety of worms, including roundworms, hookworms, whipworms, and pinworms.  Mebendazole 100 mg works by inhibiting the formation of microtubules in the intestinal cells of the parasites, which disrupts their ability to absorb glucose, leading to their death. It is typically administered orally in the form of tablets or chewable tablets, with dosages varying depending on the type and severity of the infection. Common regimens include a single dose or a course of several days. Mebendazole is generally well-tolerated, with side effects being mild and uncommon. Possible adverse reactions include abdominal pain, diarrhea, nausea, and, rarely, headache or rash. It is usually contraindicated in patients with known hypersensitivity to the drug. Care should be taken when prescribing it during pregnancy, especially in the first trimester. Beyond its use for individual treatment, mebendazole is sometimes employed in mass deworming programs in endemic areas to reduce the prevalence of parasitic infections. Proper hygiene, sanitation, and follow-up treatment are recommended to prevent reinfection. Mebendazole remains a safe and effective option for managing intestinal worm infections in humans.
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