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Biohybrid systems represent a groundbreaking fusion of biology and engineering, where living cells are integrated with synthetic components to create responsive, functional machines. These systems range from soft robotics powered by muscle cells to bio-computers using neural networks. This topic explores how scientists are leveraging cellular behavior for applications in medicine, environmental sensing, and micro-scale robotics. We’ll examine fabrication methods, ethical considerations, and real-world implementations that push the boundary between living organisms and artificial devices. As biology meets tech, the line between natural and synthetic grows intriguingly thin—and full of potential.